Draft placeholder. This Methods page summarises the internal controlling Master Prompt (v1.9) at a high level. A fully author-approved public Methods document will replace this draft.
Scope
The library covers 18 categories and 175 topics spanning foundational stem-cell biology; established versus experimental therapies; mesenchymal stromal/stem-cell biology; umbilical-cord tissue and cord blood; MSC collection, culture, and quality; exosomes and extracellular vesicles; mechanisms of action; potential applications by condition; clinical-trial evidence and grading; dosing and administration; safety and contraindications; manufacturing standards; regulation; ethics and informed consent; patient selection; recognising misleading claims; questions patients should ask; and emerging research.
Source selection
- Primary and secondary literature is selected on a per-topic basis under a Structured Educational Evidence Review approach: purposeful, saturation-stopped, and transparent about what was and was not included.
- Where regulatory authorities (FDA, EMA, MHRA, PMDA, ICH) have issued guidance, that guidance is cited directly.
- Non-peer-reviewed sources are used only when they are the authoritative source for an administrative or regulatory fact.
Writing conventions
- Professional editions are evidence-led, mechanistic, and explicitly uncertainty-aware.
- Patient editions translate the same scientific posture into plain language without softening the evidence boundaries.
- Controlled Glossary terms are bolded at first body use within each edition; a per-topic Glossary registry is published with the article.
- Figures are coordinated to the topic's controlling points and are not reused across topics. No stock photography of patients or clinicians is used in educational figures.
Verification and approval
- Each topic is drafted against its controlling points and literature.
- A source-by-source scientific proof confirms that each claim is supported by its citation.
- A public-facing wording and grammar proof confirms that the Professional and Patient editions remain mutually consistent.
- Figures and tables undergo a geometry, containment, and colour audit; crimson table headers use white #FFFFFF on crimson #7A1533.
- A final per-topic approval is recorded. Only approved topics are visible on steamcell.com/library; pending topics are not indexed and are not discoverable.
Updates and versioning
Each topic carries its own most recent literature review date. Material changes are versioned, with the superseded version preserved in the production record. Minor copy edits do not change the review date.
Independence
The library does not accept product sponsorship, placement, or promotional partnerships. It does not promote any specific clinic, product, or procedure. The author's clinical practice is listed on the clinic site; it is intentionally separated from the library's editorial content.
Corrections
Readers who spot an error are invited to contact the editorial team through the clinic contact page. Corrections are documented in the topic's version history.